Cytogenetic Testing Centre in Gurgaon

Cytogenetic Testing Centre in Gurgaon: Cytogenetic Testing is the type of medical test that examines the chromosomes of cells for abnormalities such as aneuploidy and structural abnormalities. Chromosomes carry the genetic material of an organism  (deoxyribonucleic acid [DNA]) that contains 23 pairs of chromosomes, including 22 pairs of autosomes and a pair of sex chromosomes (XX or XY). Chromosomes carry all the genetic information required for each cell in the body to function properly.

Narula Diagnostics Centre is a Trusted Cytogenetic Testing Centre in Gurgaon that diagnoses various genetic disorders, determines the cause of developmental delays or birth defects, and assesses the risk of certain conditions such as developmental delay, congenital defects, and abnormal bodily function. Furthermore, Cytogenetic tests are a crucial part of a leukemia diagnosis. Usually, Leukemia is first diagnosed using other tests, including:

• It is a physical exam where the doctor checks for leukemia symptoms.
• This test measures the levels of each type of blood cell (CBC)
• A peripheral blood smear, in which a doctor closely tests blood cells under a microscope to look for abnormalities
• This test involves a small sample of cells is taken from the bone marrow (tissue inside of certain bones) to look for cancer cells there

Diffrent Structural abnormalities are:

• Duplication: part of chromosome repeated again and again.
• Deletion: Part of a chromosome is missing in cells.
• Translocation: Material between two different chromosomes is exchanged.
• Insertion: Addition of material from another chromosome.
• Inversion: Part of the chromosome is inverted within the chromosome.

Meaning and Types of Cytogenetic Testing

Cytogenetic testing involves the analysis of cells in a sample of blood, amniotic fluid, tissue, and bone marrow to detect any change in a person’s chromosomes, There are diffrent types of cytogenetic tests, including:

Karyotyping

Karyotyping is one of the most preferred test methods that include staining and examining a sample of cells. It is typically obtained from blood or amniotic fluid to visualize the chromosomes under a microscope. Kayotyping can disclose abnormalities in DNA or fetus such as translocations,  extra or missing chromosomes, duplications, and deletions. Furthermore, implementing the G-banding technique, and analyzing 20 metaphase-state cells is the best method for karyotyping. If mosaicism is suspected, 30 to 50 metaphases should be analyzed.

Fluorescence In Situ Hybridization (FISH)

The effective cytogenetic technique “FISH” uses fluorescently labeled DNA probes to target particular locations of chromosomes. Generally, it can be performed interphase stage help to detect specific genetic abnormalities like gene amplifications or chromosomal rearrangement in human cells. Fluorescence In Situ Hybridization (FISH) can be performed on cells obtained from several sources such as tissue samples, blood, and amniotic fluid but it does not analyze the full set of chromosomes

Comparative Genomic Hybridization (CGH)

It is an advanced molecular cytogenetic technique that helps to DNA copy numbers between two different samples- reference sample and patient sample. Cytogenetic Testing Centre in Gurgaon used this technology(CGH)  to detect chromosomal imbalances like duplications, deletion, and amplifications, across the complete genome. CGH can be performed on cells produced from different sources like blood, tissue samples, and amniotic fluid.

Chromosomal Microarray Analysis (CMA)

CMA (Chromsosmal Microarray Analysis)  is a high-resolution new technology that implements microarrays to analyze DNA copy number variations across the genome. It helps to detect submicroscopic chromosomal imbalances like microduplications and microdeletions that are invisible in traditional karyotyping. Often CMA is used to evaluate developmental disorders, intellectual disabilities, and autism spectrum disorder.

Why I need Cytogenetic Testing

Look below the several reasons why a person might need cytogenetic testing, which involves the analysis of chromosomes in cells.

• Birth Defects: If you or your child have been diagnosed with birth defects or developmental delays, cytogenetic testing may be recommended.
• Recurrent Miscarriages: Couples who face recurrent miscarriages are recommended for cytogenetic testing.
• Family History of Genetic Disorder: If the patient has a family history of chromosomal abnormalities or genetic disorders, they must to go Cytogenetic Testing Centre in Gurgaon.
• High-Risk Pregnancy Factors: If women suffer during the pregnancy period to screen or face diagnosed abnormalities in the fetus, increased risk based on maternal age, abnormal prenatal screening result, or a family history of the genetic disorder,  particularly in this case it is recommended for cytogenetic testing.
• Hematological cancer- Generally performed in cancer patients to identify chromosomal abnormalities and genetic mutations linked with the development and progression of cancer.

Trusted Cytogenetic Testing Centre in Gurgaon

Narula Diagnostics Centre is a well-reputed name in the industry known for reliable  NABL-certified cytogenetic testing services. Cytogenetic Testing Centre in Gurgaon is backed by a skilled team of cytogenetics technologists that is proficient in using advanced tools and techniques to conduct accurate cytogenetic tests. Apart from this, they serve over 5 core patients with a broad menu of 2500+ affordable health test packages. Genuine Lab in Gurugram provides online access to reports on guaranteed time.

• Latest Equipements to conduct accurate procedure.
• Home Sample Collection service offered by Narula Diagnostics Centre.
• Convenient and time-saving
• If youn have any questions don’t hesitate to call the team at Narula Diagnostics Centre.